Search on: OROTIDINE PHOSPHATE CARBOXY-LYASE 
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Descriptor English:   Orotidine-5'-Phosphate Decarboxylase 
Descriptor Spanish:   Orotidina-5'-Fosfato Descarboxilasa 
Descriptor Portuguese:   Orotidina-5'-Fosfato Descarboxilase 
Synonyms English:   Orotidine Phosphate Carboxy-Lyase
Orotidylate Decarboxylase  
Tree Number:   D08.811.520.224.125.450
Definition English:   Orotidine-5'-phosphate carboxy-lyase. Catalyzes the decarboxylation of orotidylic acid to yield uridylic acid in the final step of the pyrimidine nucleotide biosynthesis pathway. EC 4.1.1.23. 
Indexing Annotation English:   /defic: consider also OROTIC ACID /urine (IM) + PURINE-PYRIMIDINE METABOLISM, INBORN ERRORS (IM); DF: OMP DECARBOXYLASE
History Note English:   91(77); was see under CARBOXY-LYASES 1977-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   10142 
Unique Identifier:   D009964 

Occurrence in VHL:
 

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